Role of P-glycoprotein in the pharmacotherapy of pregnant women
This review addresses the function of 9x11 pergola the protein-transporter glycoprotein-P (Pgp, ABCB1 protein) and the expression of its encoding gene MDR1/mdr1 throughout the gestational period in humans and animals.We discuss the relationship between the transporter function and the hormone fluctuations during pregnancy.We cite studies on the ass